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Single-Cell Analysis Technologies for Immuno-Oncology Research: From Mechanistic Delineation to Biomarker Discovery

1 Apr 2021

Abstract excerpt

The successes with immune checkpoint blockade (ICB) and chimeric antigen receptor (CAR)-T-cell therapy in treating multiple cancer types have established immunotherapy as a powerful curative option for patients with advanced cancers. Unfortunately, many patients do not derive benefit or long-term responses, highlighting a pressing need to perform complete investigation of the underlying mechanisms and the...

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PMID: 34000441
DOI: 10.1016/j.gpb.2021.02.004

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