Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deciphering and advancing CAR T-cell therapy with single-cell sequencing technologies

6 May 2023

Abstract excerpt

Chimeric antigen receptor (CAR) T-cell therapy has made remarkable progress in cancer immunotherapy, but several challenges with unclear mechanisms hinder its wide clinical application. Single-cell sequencing technologies, with the powerful unbiased analysis of cellular heterogeneity and molecular patterns at unprecedented resolution, have greatly advanced our understanding of immunology and oncology. In this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Nanowire Synthesis and Applications
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37149643
DOI: 10.1186/s12943-023-01783-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deciphering and advancing CAR T-cell therapy with single-cell sequencing technologiesPMID 37149643Read ↗

High-throughput single-сell sequencing in cancer researchSemantic proximity Read ↗

Application of single-cell sequencing to the research of tumor microenvironmentSemantic proximity Read ↗

Integrative insights and clinical applications of single-cell sequencing in cancer immunotherapySemantic proximity Read ↗

Understanding Mechanisms of Response to CAR T-cell Therapy through Single-Cell Sequencing: Insights and ChallengesSemantic proximity Read ↗

Harnessing the Transcriptional Signatures of Car-T Cells and Leukemia/Lymphoma Using Single-Cell Sequencing TechnologiesSemantic proximity Read ↗

Single-Cell Analysis Technologies for Immuno-Oncology Research: From Mechanistic Delineation to Biomarker DiscoverySemantic proximity Read ↗

Single-Cell Sequencing: Current Applications in Precision Onco-Genomics and Cancer TherapeuticsSemantic proximity Read ↗

From Oncogenic Signaling Pathways to Single-Cell Sequencing of Immune Cells: Changing the Landscape of Cancer ImmunotherapySemantic proximity Read ↗

Single-Cell Sequencing for Precise Cancer Research: Progress and ProspectsSemantic proximity Read ↗

Immunotherapy of cancer in single-cell RNA sequencing era: A precision medicine perspectiveSemantic proximity Read ↗

Single-Cell Sequencing in Cancer: Recent Applications to Immunogenomics and Multi-omics ToolsSemantic proximity Read ↗

Single-cell multi-omics in cancer immunotherapy: from tumor heterogeneity to personalized precision treatmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.