Article

Kismet/CHD7/CHD8 affects gut biomechanics, the gut microbiome, and gut-brain axis in <i>Drosophila melanogaster</i>

2021-12-17

Abstract excerpt

The gut-brain axis may contribute to the pathophysiology of neurodevelopmental disorders, yet it is often unclear how risk genes associated with these disorders affect gut physiology in a manner that could impact microbial colonization. We addressed this question using Drosophila melanogaster with a null mutation in kismet, the ortholog of chromodomain helicase DNA-binding protein ( CHD ) family members CHD7 a...

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Identifiers and source

Literature Corpus work: 7c717186-9f53-5daf-91dd-c703b588a790
DOI: 10.1101/2021.12.17.473216

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