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A shared chromosome 12 rare-variant locus links sudden sensorineural hearing loss, vestibular neuritis, and serum potassium homeostasis

2026-08-25

Abstract excerpt

<title>Abstract</title> <p> <bold>Purpose</bold> : Sudden sensorineural hearing loss (SSNHL) and vestibular neuritis (VN) are acute inner-ear disorders of unknown etiology. A missense variant near TUBA1C has been linked to both in Finland, but the shared causal architecture is undefined. We sought to resolve the causal signal, prioritize the causal gene, and identify a clinical correlate. <bold>Methods</bold>...

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Literature Corpus work
7c591d1a-00a9-54a7-83c3-13293c5b76ff
DOI
10.21203/rs.3.rs-10793773/v1
Open publication

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A shared chromosome 12 rare-variant locus links sudden sensorineural hearing loss, vestibular neuritis, and serum potassium homeostasisDOI 10.21203/rs.3.rs-10793773/v1
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