Article

Transient K <sup>+</sup> current explains cross-species differences in the effects of myofibroblasts on myocytes

2020-11-02

Abstract excerpt

Electrical and paracrine couplings between cardiomyocytes (CMs) and myofibroblasts (MFBs) affect both physiology and pathophysiology of cardiac tissues in a range of animal models, but relating these observations to humans is a challenge because effects vary greatly across species. To address this challenge, we developed a mathematical model for mechanoelectrical interactions between CM and MFB, considering both e...

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Literature Corpus work: 7c3c0255-bc7d-5179-86d5-3a9acabe051f
DOI: 10.1101/2020.11.02.365650

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