Article

Promoter Methylation of the MGRN1 Gene Response to Chemotherapy of Epithelial Ovarian Cancer Patients

2021-03-16

Abstract excerpt

<h4>Objective: </h4> Aberrant DNA methylation is considered to play a critical role in the chemoresistance of epithelial ovarian cancer (EOC). In this study, we explored the relationship between hypermethylation of the Mahogunin Ring Finger 1 ( MGRN1 ) gene promoter and primary chemoresistance in EOC patients. <h4>Methods: </h4>: Hypermethylation of the MGRN1 promoter region in the cancer tissues of platinum-resis...

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Literature Corpus work: 7c2b867d-5afa-53ca-91a5-76a5256ec3c8
DOI: 10.21203/rs.3.rs-298962/v1

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