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A Simulation of Semi-Infectious Particles and Genome Complementation Reproduces Interferon Response by Respiratory Epithelial Cells <i>in vitro</i> during Influenza A Virus Infection

2026-05-22

Abstract excerpt

In the respiratory epithelium, interferon (IFN)-induced antiviral resistance acts as a defense against infection. Influenza A viruses (IAVs) have evolved multiple strategies to counteract these defenses, including expression of the viral protein NS1, which inhibits both IFN production and the IFN-mediated transcription of Interferon Stimulated Genes (ISG) in infected cells. However, experiments show that this inhi...

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Literature Corpus work
7c22140a-ce60-56a6-aa7a-fe7ba55f0267
DOI
10.64898/2026.05.20.726376
Open publication

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