Article

Nrf2 represses ER stress-related ferroptosis in renal carcinoma cells via HO-1

2020-03-05

Abstract excerpt

Selective-induction of regulated cell death is considered as a useful strategy for developing effective therapies against renal cell carcinoma (RCC). In this study, the role of nuclear factor-E2-related factor 2 (Nrf2) and its downstream genes in erastin-induced ferroptosis of renal carcinoma cells was investigated. Erastin induced endoplasmic reticulum (ER) stress and ferroptosis in renal carcinoma cells (786-0 a...

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Literature Corpus work: 63aba38d-e991-55fa-9cc3-15b10c0394fc
DOI: 10.1101/2020.03.04.977769

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