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Article

A Comprehensive Review on the Genetic Regulation of Cisplatin-induced Nephrotoxicity

29 Mar 2016

Abstract excerpt

Cisplatin (CDDP) is a well-known antineoplastic drug which has been extensively utilized over the last decades in the treatment of numerous kinds of tumors. However, CDDP induces a wide range of toxicities in a dose-dependent manner, among which nephrotoxicity is of particular importance. Still, the mechanism of CDDP-induced renal damage is not completely understood; moreover, the knowledge about the role of...

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PMID: 27252593
DOI: 10.2174/1389202917666160202220555

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