Article

Steroidogenic factor 1 promotes cuproptosis in renal tubular epithelial cells during acute kidney injury

2023-06-15

Abstract excerpt

<title>Abstract</title><p>Programmed cell death of renal tubular epithelial cells (RTECs) is the main pathophysiological mechanism of acute kidney injury (AKI). Copper-induced death is a newly discovered form of programmed cell death, mainly attributed to fatty acylation in the TCA cycle, which leads to mitochondrial stress and cell death. However, the role of copper-induced death in the occurrence and development...

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Literature Corpus work: 0e290cb8-721a-59be-9306-690cbe57fafd
DOI: 10.21203/rs.3.rs-3048107/v1

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