Article

The role of CD40 in the immune response

1999-01-01

Abstract excerpt

A successful humoral immune response requires reciprocal signaling between T helper cells and B cells. The first signal is antigen specific and is mediated by the interaction between the T cell receptor and antigen in association with major histocompatibility complex on B cells. The subsequent signals are provided by the costimulatory molecules CD40 and CD28 and their respective ligands. CD40L which is expressed o...

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Literature Corpus work: 7b98ecf0-01c6-55e6-9b9e-4260af3ad019
DOI: 10.21954/ou.ro.00010250

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