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Article

Central role of CD40 and its ligand in B lymphocyte responses to T-dependent antigens.

Cellular and molecular biology (Noisy-le-Grand, France) - 1 Jan 1994

Gordon J, Katira A, Holder M, MacDonald I, Pound J

Abstract excerpt

In order to mount an effective antibody response to soluble and certain other types of antigens, B cells need help from T cells. Recently, an important receptor-ligand pair has been identified as essential for successful cognate interaction between these two classes of lymphocytes. CD40 was first identified as a receptor-like molecule on B cells which when ligated by antibody could deliver signals to prime for...

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PMID: 7524882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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