Article

Development of a novel mechanism-based glycolipid adjuvant for vaccination

2018-05-30

Abstract excerpt

The inability to elicit strong and durable cellular responses is a major obstacle in the development of successful vaccines, in particular those against malaria. In this regard, the generation of novel adjuvants that will potently boost cell-mediated immunity induced by candidate vaccines is helpful. We and others have found a glycolipid, called α-galactosylceramide (α-GalCer), which could be presented on CD1d exp...

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Literature Corpus work: 7b7cdd17-065f-5293-811b-e244faebc2a4
DOI: 10.12688/f1000research.13794.1

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