Article

Boosting Live Malaria Vaccine with Cytomegalovirus Vector Can Prolong Immunity through Innate and Adaptive Mechanisms

2023-05-02

Abstract excerpt

Vaccines to persistent parasite infections have been challenging, and current iterations lack long-term protection. Cytomegalovirus ( CMV) chronic vaccine vectors drive protection against SIV, tuberculosis and liver-stage malaria correlated with antigen-specific CD8 T cells with a Tem phenotype. This phenotype is likely driven by a combination of antigen-specific and innate adjuvanting effects of the vector, thou...

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Literature Corpus work: 45d94497-a2e4-5868-9857-44db17ef8b64
DOI: 10.1101/2023.05.02.539025

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