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Article

GMMA-Based Vaccines: The Known and The Unknown

3 Aug 2021

Abstract excerpt

Generalized Modules for Membrane Antigens (GMMA) are outer membrane vesicles derived from Gram-negative bacteria engineered to provide an over-vesiculating phenotype, which represent an attractive platform for the design of affordable vaccines. GMMA can be further genetically manipulated to modulate the risk of systemic reactogenicity and to act as delivery system for heterologous polysaccharide or protein...

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PMID: 34413858
DOI: 10.3389/fimmu.2021.715393

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