Article

SMAP: exploiting high-throughput sequencing data of patient derived xenografts

2018-10-11

Abstract excerpt

<h4>Background</h4> Patient-derived xenograft is the model of reference in oncology fordrug response analyses. Xenografts samples have the specificity to be composedof cells from both the graft and the host species. Sequencing analysis ofxenograft samples therefore requires specific processing methods to properlyreconstruct genomic profiles of both the host and graft compartments. <h4>Results</h4> We propose a n...

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Literature Corpus work: 7b73e8b8-3497-5883-92ee-a1ea54542de1
DOI: 10.1101/440008

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