Article

XenoCell: classification of cellular barcodes in single cell experiments from xenograft samples

2019-06-21

Abstract excerpt

Single-cell sequencing technologies provide unprecedented opportunities to deconvolve the genomic, transcriptomic or epigenomic heterogeneity of complex biological systems. Its application in samples from xenografts of patient-derived biopsies (PDX), however, is limited by the presence in the analysed samples of a mixture of cells arising from the host and the graft. We have developed XenoCell, the first stand-alo...

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Literature Corpus work: 642a9dc1-081f-5230-8c42-8e242fcc078b
DOI: 10.1101/679183

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