Article

The Aryl Hydrocarbon Receptor Controls IFNγ-Induced Immune Checkpoints PD-L1 and IDO via the JAK/STAT Pathway in Lung Adenocarcinoma

2024-08-13

Abstract excerpt

While immunotherapy has shown efficacy in lung adenocarcinoma (LUAD) patients, many respond only partially or not at all. One limitation in improving outcomes is the lack of a complete understanding of immune checkpoint regulation. Here, we investigated a possible link between an environmental chemical receptor implicated in lung cancer and immune regulation, ( the aryl hydrocarbon receptor/AhR), a known but coun...

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Literature Corpus work: 7b5f51ab-7301-5d84-b987-0422eb98c011
DOI: 10.1101/2024.08.12.607602

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