Article

Altered Hippocampal Structure-Function Coupling and Brain-Cognition Aging Profile in Mild Cognitive Impairment

2026-06-24

Abstract excerpt

Hippocampal atrophy and altered functional connectivity are prominent features of mild cognitive impairment (MCI), yet their relationships and joint contribution to cognitive impairment remain unclear. We evaluated multidomain cognitive-sensorimotor performance, whole-brain gray matter atrophy patterns, associated functional connectivity, and their coupling in MCI and HC. We conducted this cross-sectional study in...

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Literature Corpus work: 7b3e7519-c652-58f0-b858-dfe8f4366fa9
DOI: 10.64898/2026.06.19.733422

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