Article

Striatin plays a major role in angiotensin II-induced cardiomyocyte and cardiac hypertrophy in mice <i>in vivo</i>

2023-10-24

Abstract excerpt

The three striatins (STRN, STRN3, STRN4) form the core of STR iatin- I nteracting P hosphatase and K inase (STRIPAK) complexes. These place protein phosphatase 2A (PP2A) in proximity to protein kinases thereby restraining kinase activity and regulating key cellular processes. Our aim was to establish if striatins play a significant role in cardiac remodelling associated with cardiac hypertrophy and heart failu...

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Literature Corpus work: 7b3d2e43-5d1e-5340-ac29-8076c24aa501
DOI: 10.1101/2023.10.21.563397

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