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Aldosterone's Rapid, Nongenomic Effects Are Mediated by Striatin: A Modulator of Aldosterone's Effect on Estrogen Action

21 Mar 2014

Abstract excerpt

The cellular responses to steroids are mediated by 2 general mechanisms: genomic and rapid/nongenomic effects. Identification of the mechanisms underlying aldosterone (ALDO)'s rapid vs their genomic actions is difficult to study, and these mechanisms are not clearly understood. Recent data suggest that striatin is a mediator of nongenomic effects of estrogen. We explored the hypothesis that striatin is an...

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PMID: 24654783
DOI: 10.1210/en.2013-1834

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