Article

Genome-wide identification of functional tRNA-derived fragments in Senescence-accelerated mouse prone 8 brain

2018-06-15

Abstract excerpt

tRNA-derived fragments (tRFs) have been linked previously to the development of various diseases, such as cancer and viral infection. However, tRFs seem also related to brain aging and related diseases, especially Alzheimer and Parkinson disease. RNA sequencing, a state-of-the-art technology, has allowed for investigation of tRFs in this field. In this study, we investigated the changes of tRFs in the brains of a...

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Literature Corpus work: 7b305e71-ffe7-5a6a-8ea7-ba0e54406972
DOI: 10.1101/348300

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