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Mitochondria Localized microRNAs: An Unexplored miRNA Niche in Alzheimer’s Disease and Aging

25 Feb 2023

Abstract excerpt

homeostasis, Reactive Oxygen Species (ROS) production, apoptosis, mitophagy, axonal transport and neurotransmission. Mitochondrial dysfunction is a well-established phenomenon in the pathophysiology of many neurological diseases, including Alzheimer's disease (AD). Amyloid-beta (Aβ) and Phosphorylated tau (p-tau) proteins cause the severe mitochondrial defects in AD. A newly discovered cellular niche of microRNAs...

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PMID: 36899879
DOI: 10.3390/cells12050742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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