Article
Determination of the genetic mechanisms responsible for generating diversity in the cattle NK cell receptor repertoire
2014-01-01
Abstract excerpt
Cattle have expanded the KIR gene repertoire, a polymorphic and polygenic im- munoglobulin family that encode Natural Killer cell receptors specific to MHC class I ligands. In humans, KIR are important mediators of innate immunity to viral pathogens such as HCV and HIV, and there is potential for exploiting cattle KIR diversity as a means of improving animal health. Cattle KIR expansion has occurred independently...
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Identifiers and source
- Literature Corpus work
- 7b125f97-842c-5bb7-a790-c87e250316d5
- DOI
- 10.25560/25092