Article
Cattle NK Cell Heterogeneity and the Influence of MHC Class I.
Journal of immunology (Baltimore, Md. : 1950) - 1 Sept 2015
Allan Alasdair J, Sanderson Nicholas D, Gubbins Simon, Ellis Shirley A, Hammond John A
Abstract excerpt
Primate and rodent NK cells form highly heterogeneous lymphocyte populations owing to the differential expression of germline-encoded receptors. Many of these receptors are polymorphic and recognize equally polymorphic determinants of MHC class I. This diversity can lead to individuals carrying NK cells with different specificities. Cattle have an unusually diverse repertoire of NK cell receptor genes predicted...
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