Article

Improved immunoassay sensitivity and specificity using single-molecule colocalization

2021-12-25

Abstract excerpt

Enzyme-linked immunosorbent assays (ELISAs) are a cornerstone of modern molecular detection, but the technique still suffers some notable challenges. One of the biggest problems is discriminating true signal generated by target molecules versus non-specific background arising from the interaction of detection antibodies with the assay substrate or interferents in the sample matrix. Si ngle- M olecule C olocaliz...

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Literature Corpus work: 7adbe6e0-f6a7-58ff-b4aa-167b27e68e39
DOI: 10.1101/2021.12.24.474141

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