Article
Highly Accurate Profiling of Exosome Phenotypes Using Super-resolution Tricolor Fluorescence Co-localization.
ACS nano - 9 Apr 2024
Wei Jinxiu, Zhu Kai, Wang Tingyu, Qi Tongsheng, Wang Zhuyuan, Li Jia, Zong Shenfei, Cui Yiping
Abstract excerpt
Exosomes contain a wealth of proteomic information, presenting promising biomarkers for the noninvasive early diagnosis of diseases, especially cancer. However, it remains a great challenge to accurately and reliably distinguish exosomes secreted from different types of cell lines. Fluorescence immunoassay is frequently used for exosome detection. Nonspecific adsorption in immunoassays is unavoidable and affects...
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