Article

HBV Pre-S1-Derived Myristoylated Peptide (Myr47): Identification of the Inhibitory Activity on the Cellular Uptake of Lipid Nanoparticles

2021-04-19

Abstract excerpt

Myr47 lipopeptide consisting of hepatitis B virus (HBV) pre-S1 domain (myristoylated 2-48 peptide) is a commercialized effective anti-HBV drug, preventing the interaction of HBV with sodium taurocholate cotransporting polypeptide (NTCP) on human hepatocytes, of which the activity requires both N-myristoylation residue and specific amino acid sequence. Meanwhile, we recently reported that Myr47 reduces the cellular...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7ab72efe-d6c2-5c6e-95e5-1d39910e998f
DOI: 10.20944/preprints202104.0512.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

HBV Pre-S1-Derived Myristoylated Peptide (Myr47): Identification of the Inhibitory Activity on the Cellular Uptake of Lipid NanoparticlesDOI 10.20944/preprints202104.0512.v1Read

Envelope Proteins of Hepatitis B Virus: Molecular Biology and Involvement in Carcinogenesis.Semantic proximity Read

Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface protein.Semantic proximity Read

Mutational analysis of hepatitis B virus pre-S1 (9-24) fusogenic peptide.Semantic proximity Read

Bacterial expression, purification, and in vitro N-myristoylation of fusion hepatitis B virus preS1 with the native-type N-terminus.Semantic proximity Read

Effective Therapeutic Drug Delivery by GALA3, an Endosomal Escape Peptide with Reduced Hydrophobicity.Semantic proximity Read

Subversion of cellular autophagy machinery by hepatitis B virus for viral envelopment.Semantic proximity Read

Structure of hepatitis B/D antiviral drug Bulevirtide bound to its receptor protein NTCPSemantic proximity Read

Low immunogenic bio-nanocapsule based on hepatitis B virus escape mutants.Semantic proximity Read

Palmitoylation of hepatitis C virus core protein is important for virion production.Semantic proximity Read

Structure of the bile acid transporter and HBV receptor NTCP.Semantic proximity Read

Sodium Taurocholate Cotransporting Polypeptide Mediates Woolly Monkey Hepatitis B Virus Infection of Tupaia HepatocytesSemantic proximity Read

N-terminal myristoylation-dependent masking of neutralizing epitopes in the preS1 attachment site of hepatitis B virus.Semantic proximity Read