Article

Identification of type 2 diabetes- and obesity-associated human β-cells using deep transfer learning

2024-01-23

Abstract excerpt

<h4>ABSTRACT</h4> Diabetes affects >10% of adults worldwide and is caused by impaired production or response to insulin, resulting in chronic hyperglycemia. Pancreatic islet β-cells are the sole source of endogenous insulin and our understanding of β-cell dysfunction and death in type 2 diabetes (T2D) is incomplete. Single-cell RNA-seq data supports heterogeneity as an important factor in β-cell function and surv...

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Literature Corpus work: 7a6ae86e-62f5-5904-a4a6-533d9c0b9883
DOI: 10.1101/2024.01.18.576260

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