Article
<i>Ubc9</i> deletion in adipocytes causes lipoatrophy in mice
2020-09-12
Abstract excerpt
<h4>ABSTRACT</h4> <h4>Objective</h4> White adipose tissue (WAT) expansion regulates energy balance and overall metabolic homeostasis. WAT absence or loss occurring through lipodystrophy and lipoatrophy contributes to the development of dyslipidemia, hepatic steatosis, and insulin resistance. We previously demonstrated the sole small ubiquitin-like modifier (SUMO) E2-conjuguating enzyme Ubc9 represses human adipo...
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Identifiers and source
- Literature Corpus work
- 7a3d57fa-fb35-5bed-bd55-4ef61c7d4d0b
- DOI
- 10.1101/2020.09.12.294629