Article
Long noncoding RNAs regulate adipogenesis.
Proceedings of the National Academy of Sciences of the United States of America - 26 Feb 2013
Sun Lei, Goff Loyal A, Trapnell Cole, Alexander Ryan, Lo Kinyui Alice, Hacisuleyman Ezgi, Sauvageau Martin, Tazon-Vega Barbara, Kelley David R, Hendrickson David G, Yuan Bingbing, Kellis Manolis, Lodish Harvey F, Rinn John L
Abstract excerpt
The prevalence of obesity has led to a surge of interest in understanding the detailed mechanisms underlying adipocyte development. Many protein-coding genes, mRNAs, and microRNAs have been implicated in adipocyte development, but the global expression patterns and functional contributions of long noncoding RNA (lncRNA) during adipogenesis have not been explored. Here we profiled the transcriptome of primary...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.