Article

In silico and functional analysis of genomic aberrations associated with pancreatic and ovarian cancers

2017-01-01

Abstract excerpt

High grade serous (HGS) ovarian cancer and pancreatic ductal adenocarcinoma (PDAC) are poor prognosis neoplasms that are characterised by high levels of genomic instability, DNA damage repair (DDR) defects, and drug resistance which ultimately results in poor survival rates. This study aims to use markers of genomic instability, in the form of copy number variations (CNVs) and gene expression changes, to identify...

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Literature Corpus work: 7a3d2f21-8139-5489-b679-a6faccc9e582
DOI: 10.25560/49207

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