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Genome-wide analysis of copy number alterations led to the characterisation of PDCD10 as oncogene in ovarian cancer

27 Jan 2021

Abstract excerpt

Copy Number Alterations (CNAs) represent the most common genetic alterations identified in ovarian cancer cells, being responsible for the extensive genomic instability observed in this cancer. Here we report the identification of CNAs in a cohort of Italian patients affected by ovarian cancer performed by SNP-based array. Our analysis allowed the identification of 201 significantly altered chromosomal bands (70...

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PMID: 33516089
DOI: 10.1016/j.tranon.2021.101013

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