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Article

Functional regulations between genetic alteration-driven genes and drug target genes acting as prognostic biomarkers in breast cancer.

Scientific reports - 23 Jun 2022

Wang Li, Yu Lei, Shi Jian, Li Feng, Zhang Caiyu, Xu Haotian, Yin Xiangzhe, Wang Lixia, Lin Shihua, Litvinova Anastasiia, Ping Yanyan, Ning Shangwei, Zhao Hongying

Abstract excerpt

Differences in genetic molecular features including mutation, copy number alterations and DNA methylation, can explain interindividual variability in response to anti-cancer drugs in cancer patients. However, identifying genetic alteration-driven genes and characterizing their functional mechanisms in different cancer types are still major challenges for cancer studies. Here, we systematically identified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35739271
DOI: 10.1038/s41598-022-13835-5
PMCID: PMC9226112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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