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Changes in methylation-based aging in women who do and do not develop breast cancer

24 Jun 2023

Abstract excerpt

BACKGROUND: Breast cancer survivors have increased incidence of age-related diseases, suggesting that some survivors may experience faster biological aging. METHODS: Among 417 women enrolled in the prospective Sister Study cohort, DNA methylation data were generated on paired blood samples collected an average of 7.7 years apart and used to calculate 3 epigenetic metrics of biological aging (PhenoAgeAccel,...

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PMID: 37467056
DOI: 10.1093/jnci/djad117

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