Article

Elucidating the molecular interactions between uremic toxins and the Sudlow II binding site of human serum albumin

2020-02-20

Abstract excerpt

Protein bound uremic toxins (PBUTs) are known to bind strongly with the primary drug carrying sites of human serum albumin (HSA), Sudlow site I and Sudlow site II. A detailed energetic and structural description of PBUT interactions with these binding sites would provide useful insight into the design of materials that specifically displace and capture PBUTs. In this work, we used molecular dynamics (MD) simulatio...

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Literature Corpus work: 7a1492c3-f339-50bb-b8ca-69ed0a19a9f9
DOI: 10.1101/2020.02.19.940171

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