Article

Binding of anticaries agent Chelorhexidine to Human Serum Albumin as vehicle for antibacterial purposes: Experimental and Molecular Docking Assessments

2025-12-16

Abstract excerpt

<title>Abstract</title> Human serum albumin (HSA) was used for targeted drug delivery that can enhance the pharmacokinetics, targetability, solubility, and stability of various therapeutic agents. The objective is the interaction studies of chelorhexidine drug, used extensively in oral hygiene for preventing dental plaque and treating infections of the mouth, with HSA. Fluorescence quenching assays, UV-visible...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8a5a0838-c320-5eed-b4b2-934276ed6395
DOI: 10.21203/rs.3.rs-7699264/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Binding of anticaries agent Chelorhexidine to Human Serum Albumin as vehicle for antibacterial purposes: Experimental and Molecular Docking AssessmentsDOI 10.21203/rs.3.rs-7699264/v1Read

Role of Non-ionic surfactant on the interaction of drugs with Bovine serum albumin (BSA)Semantic proximity Read

Spectroscopic analysis of human serum albumin nanoparticles with encapsulated phenothiazine derivative (6-acetylaminobutyl-9-chloroquino[3,2-b]benzo[1,4]thiazine) – continuation studiesSemantic proximity Read

Spectroscopic Evaluation of Chalcone Derivatives and their Zinc Metal Complexes: A Combined Experimental and Computational Approach on the Binding of the Complexes with the Serum AlbuminSemantic proximity Read

Elucidating the molecular interactions between uremic toxins and the Sudlow II binding site of human serum albuminSemantic proximity Read

Profiling the Interaction between Human Serum Albumin and Clinically Relevant HIV Reverse Transcriptase InhibitorsSemantic proximity Read

Differential effects of methoxy group on the interaction of curcuminoids with two major ligand binding sites of human serum albumin.Semantic proximity Read

Development and Validation Molecular Docking Analysis of Human serum albumin (HSA)Semantic proximity Read

Arginine 485 of human serum albumin interacts with the benzophenone moiety of ketoprofen in the binding pocket of subdomain III A and III B.Semantic proximity Read

Spectroscopic Investigation of Losartan and Glipizide Competitive Binding to Glycated Albumin in Polypharmacotherapy: A Comparative StudySemantic proximity Read

In vitro and in silico identification of the mechanism of interaction of antimalarial drug – artemisinin with human serum albumin and genomic DNASemantic proximity Read

Ligand supplementation restores the cancer therapy efficacy of an antirheumatic drug auranofin from serum inactivationSemantic proximity Read

Exploring Serum Transferrin Regulation of Nonferric Metal Therapeutic Function and ToxicitySemantic proximity Read