Article

Microphysiological uremia model reveals biophysical potentiators of vascular dysfunction

2024-12-21

Abstract excerpt

Cardiovascular disease is a leading cause of mortality in individuals with chronic kidney disease. Hypertension, common among patients with chronic kidney disease, is a major contributor to both kidney damage and the heightened cardiovascular risk in these patients. Advanced chronic kidney disease is associated with elevated levels of circulating uremic toxins, particularly indoxyl sulfate and p-cresyl sulfate, an...

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Literature Corpus work: bd082c4c-d647-5713-b4be-c143fa7a472a
DOI: 10.1101/2024.12.18.629161

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