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From sequence and structure of sulfotransferases and dihydropyrimidinases to an understanding of their mechanisms of action and function.

Expert opinion on drug metabolism & toxicology - 1 May 2010

Hsu Ching-Chen, Lu Lu-Yi, Yang Yuh-Shyong

Abstract excerpt

IMPORTANCE OF THE FIELD: Most enzymes that catalyze physiologically important reactions are known to be highly efficient and specific to their particular substrates. On the contrary, the enzymes of detoxification are known to catalyze unlimited number of substrates containing similar function groups that may have significant structural variation. This review explores nature's strategy to design enzymes with...

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Identifiers

PMID: 20397966
DOI: 10.1517/17425251003601987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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