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Article

Interaction between two sulfate-conjugated uremic toxins, p-cresyl sulfate and indoxyl sulfate, during binding with human serum albumin.

Drug metabolism and disposition: the biological fate of chemicals - 1 Jul 2012

Watanabe Hiroshi, Noguchi Tsuyoshi, Miyamoto Yohei, Kadowaki Daisuke, Kotani Shunsuke, Nakajima Makoto, Miyamura Shigeyuki, Ishima Yu, Otagiri Masaki, Maruyama Toru

Abstract excerpt

Recently, p-cresyl sulfate (PCS) has been identified as a protein-bound uremic toxin. Moreover, the serum-free concentration of PCS, which is associated with its efficacy of hemodialysis, appears to be a good predictor of survival in chronic kidney disease (CKD). We previously found that PCS inte...

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PMID: 22513409
DOI: 10.1124/dmd.112.045617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22513409-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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