Article
Bridging scales in cancer progression: mapping genotype to phenotype using neural networks.
Seminars in cancer biology - 1 Feb 2015
Gerlee Philip, Kim Eunjung, Anderson Alexander R A
Abstract excerpt
In this review we summarise our recent efforts in trying to understand the role of heterogeneity in cancer progression by using neural networks to characterise different aspects of the mapping from a cancer cells genotype and environment to its phenotype. Our central premise is that cancer is an evolving system subject to mutation and selection, and the primary conduit for these processes to occur is the cancer...
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