Article

Pervasive convergent evolution and extreme phenotypes define chaperone requirements of protein homeostasis

2019-03-16

Abstract excerpt

Maintaining protein homeostasis is an essential requirement for cell and organismal viability. An elaborate regulatory system within cells, the protein homeostasis network, safeguards that proteins are correctly folded and functional. At the heart of this regulatory system lies a class of specialized protein quality control enzymes called chaperones that are tasked with assisting proteins in their folding, avoidin...

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Identifiers and source

Literature Corpus work: 79f54380-59ed-5b45-8333-b0546bf9e678
DOI: 10.1101/578724

Open publication

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