Article

The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones

2020-03-05

Abstract excerpt

The sensitivity of the protein-folding environment to chaperone disruption can be highly tissue-specific. Yet, the organization of the chaperone system across physiological human tissues has received little attention. Here, we used human tissue RNA-sequencing profiles to analyze the expression and organization of chaperones across 29 main tissues. We found that relative to protein-coding genes, chaperones were sig...

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Identifiers and source

Literature Corpus work: 3373be86-feec-53f1-8802-c35aedff0a7f
DOI: 10.1101/2020.03.04.976720

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