Article
Plasticity of the Hsp90 chaperone machine in divergent eukaryotic organisms.
Cell stress & chaperones - 1 Jan 2009
Johnson Jill L, Brown Celeste
Abstract excerpt
Hsp90 is critical for the regulation and activation of numerous client proteins critical for diverse functions such as cell growth, differentiation, and reproduction. Cytosolic Hsp90 function is dependent on a battery of co-chaperone proteins that regulate the ATPase activity of Hsp90 function or direct Hsp90 to interact with specific client proteins. Little is known about how Hsp90 complexes vary between...
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