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Article

Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms.

Annual review of genetics - 1 Jan 2010

Jarosz Daniel F, Taipale Mikko, Lindquist Susan

Abstract excerpt

Changing a single nucleotide in a genome can have profound consequences under some conditions, but the same change can have no consequences under others. Indeed, organisms can be surprisingly robust to environmental and genetic perturbations. Yet, the mechanisms underlying such robustness are con...

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Identifiers

PMID: 21047258
DOI: 10.1146/annurev.genet.40.110405.090412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21047258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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