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Article

T cell metabolic insufficiency explains the dysfunctional immune response in advanced renal cell carcinoma.

2022-12-01

Abstract excerpt

Renal cell carcinoma (RCC) is considered an immunogenic tumour with a prominent dysfunctional immune cell infiltrate, unable to control tumour growth. Although tyrosine kinase inhibitors and immunotherapy have improved the outlook for some patients, many individuals are non-responders or relapse despite treatment, and then develop progressive disease, cancer symptoms and will have a reduced life expectancy. Follow...

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Literature Corpus work
79f34a40-5f1f-5297-a05e-cf696a2c1a8f
DOI
10.21203/rs.3.rs-2320506/v1
Open publication

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T cell metabolic insufficiency explains the dysfunctional immune response in advanced renal cell carcinoma.DOI 10.21203/rs.3.rs-2320506/v1
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