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Circulating Mature Granzyme B+ T Cells Distinguish Crohn’s Disease Associated Axial Spondyloarthritis from Axial Spondyloarthritis and Crohn’s Disease

2021-01-05

Abstract excerpt

<title>Abstract</title> <bold>Background: </bold>Axial spondyloarthritis (axSpA) has strong connections with intestinal inflammation as occurs in Crohn’s disease (CD). However, the immunologic mechanisms that distinguish axSpA, CD, and those with features of both diseases (CD-axSpA) are unknown. This study aimed to address this question by initial unbiased single cell RNA-sequencing (scRNAseq) on a pilot cohor...

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Literature Corpus work: 6766b672-7edc-5368-b4f4-5a5dd1acff0d
DOI: 10.21203/rs.3.rs-138435/v1

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