Molecular Characterization of the<i>Escherichia coli</i>FimH Adhesin

Abstract excerpt

Bacterial adherence mediated by fimbriae is an essential prerequisite for colonization of the urinary tract. Uropathogenic Escherichia coli express a number of different adhesive organelles, including P, type 1, S, and F1C fimbriae [1]. Type 1, or mannose-sensitive, fimbriae are produced by >80% of all uropathogenic E. coli. It is now well established that the expression of type 1 fimbriae by E. coli is a...

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