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Tetraspanins from <i>Opisthorchis viverrini</i> stimulate cholangiocyte migration and inflammatory cytokine production

2023-06-12

Abstract excerpt

The liver fluke Opsithorchis viverrini secretes extracellular vesicles (EVs) bearing CD63-like tetraspanins on their surface. Fluke EVs are actively internalized by host cholangiocytes in the bile ducts, where they drive pathology and promote neoplasia through induction of cellular proliferation and secretion of inflammatory cytokines. We investigated the effects of tetraspanins of the CD63 superfamily by co-cult...

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Identifiers and source

Literature Corpus work
79bb1e63-2e0e-5e7c-b7d5-ffa0a35dde8e
DOI
10.1101/2023.06.12.544604
Open publication

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Tetraspanins from <i>Opisthorchis viverrini</i> stimulate cholangiocyte migration and inflammatory cytokine productionDOI 10.1101/2023.06.12.544604
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