Article

Development of Scaffold-free 3D Cholangiocyte Organoids to Study the Progression of Primary Sclerosing Cholangitis

2022-10-26

Abstract excerpt

<h4>ABSTRACT</h4> Organoids are novel in vitro models to study intercellular crosstalk between the different types of cells in the pathophysiology of disease. To better understand the underlying mechanisms driving the progression of primary sclerosing cholangitis (PSC), we developed scaffold-free multi-cellular 3D cholangiocyte organoids (3D-CHO) using ‘primary’ liver cell lines derived from normal and PSC patie...

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Literature Corpus work: bc498131-e3d1-516e-bd72-aa858ac7cfa4
DOI: 10.1101/2022.10.24.513594

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